{"id":6750,"date":"2024-04-09T13:30:59","date_gmt":"2024-04-09T13:30:59","guid":{"rendered":"https:\/\/www.solidpharma.be\/ingredient-onder-de-loep-gaba-gamma-aminoboterzuur\/"},"modified":"2024-04-11T15:48:43","modified_gmt":"2024-04-11T15:48:43","slug":"ingredient-onder-de-loep-gaba-gamma-aminoboterzuur","status":"publish","type":"post","link":"https:\/\/www.solidpharma.be\/be-fr\/ingredient-onder-de-loep-gaba-gamma-aminoboterzuur\/","title":{"rendered":"Ingr\u00e9dient \u00e0 la loupe: GABA (acide gamma-aminobutyrique)"},"content":{"rendered":"[vc_row type=&#8221;in_container&#8221; full_screen_row_position=&#8221;middle&#8221; column_margin=&#8221;default&#8221; column_direction=&#8221;default&#8221; column_direction_tablet=&#8221;default&#8221; column_direction_phone=&#8221;default&#8221; scene_position=&#8221;center&#8221; text_color=&#8221;dark&#8221; text_align=&#8221;left&#8221; row_border_radius=&#8221;none&#8221; row_border_radius_applies=&#8221;bg&#8221; overflow=&#8221;visible&#8221; overlay_strength=&#8221;0.3&#8243; gradient_direction=&#8221;left_to_right&#8221; shape_divider_position=&#8221;bottom&#8221; bg_image_animation=&#8221;none&#8221;][vc_column column_padding=&#8221;no-extra-padding&#8221; column_padding_tablet=&#8221;inherit&#8221; column_padding_phone=&#8221;inherit&#8221; column_padding_position=&#8221;all&#8221; column_element_direction_desktop=&#8221;default&#8221; column_element_spacing=&#8221;default&#8221; desktop_text_alignment=&#8221;default&#8221; tablet_text_alignment=&#8221;default&#8221; phone_text_alignment=&#8221;default&#8221; background_color_opacity=&#8221;1&#8243; background_hover_color_opacity=&#8221;1&#8243; column_backdrop_filter=&#8221;none&#8221; column_shadow=&#8221;none&#8221; column_border_radius=&#8221;none&#8221; column_link_target=&#8221;_self&#8221; column_position=&#8221;default&#8221; gradient_direction=&#8221;left_to_right&#8221; overlay_strength=&#8221;0.3&#8243; width=&#8221;1\/1&#8243; tablet_width_inherit=&#8221;default&#8221; animation_type=&#8221;default&#8221; bg_image_animation=&#8221;none&#8221; border_type=&#8221;simple&#8221; column_border_width=&#8221;none&#8221; column_border_style=&#8221;solid&#8221;][vc_column_text text_direction=&#8221;default&#8221;]\n<h4>La glutamine, l&#8217;acide glutamique et le GABA (acide gamma-aminobutyrique) sont trois acides amin\u00e9s non essentiels apparent\u00e9s qui jouent un r\u00f4le important dans le cerveau et la transmission des signaux entre les cellules nerveuses. L&#8217;acide glutamique (glutamate) peut \u00eatre converti en glutamine et en GABA. La vitamine B6 et la taurine sont des cofacteurs importants de la conversion en GABA.<\/h4>\n<h4>L&#8217;acide glutamique est un neurotransmetteur stimulant : il active la transmission de l&#8217;influx nerveux (effet excitateur).<\/h4>\n<h4>Le GABA est un neurotransmetteur calmant : il inhibe la transmission de l&#8217;influx nerveux (effet calmant), pr\u00e9vient l&#8217;hyperactivit\u00e9 c\u00e9r\u00e9brale et favorise la relaxation.<\/h4>\n<h4>La glutamine est une source d&#8217;\u00e9nergie pour le cerveau et r\u00e9gule l&#8217;activit\u00e9 de l&#8217;acide glutamique et du GABA.<\/h4>\n[\/vc_column_text][\/vc_column][\/vc_row][vc_row type=&#8221;in_container&#8221; full_screen_row_position=&#8221;middle&#8221; column_margin=&#8221;default&#8221; column_direction=&#8221;default&#8221; column_direction_tablet=&#8221;default&#8221; column_direction_phone=&#8221;default&#8221; scene_position=&#8221;center&#8221; text_color=&#8221;dark&#8221; text_align=&#8221;left&#8221; row_border_radius=&#8221;none&#8221; row_border_radius_applies=&#8221;bg&#8221; overflow=&#8221;visible&#8221; overlay_strength=&#8221;0.3&#8243; gradient_direction=&#8221;left_to_right&#8221; shape_divider_position=&#8221;bottom&#8221; bg_image_animation=&#8221;none&#8221;][vc_column column_padding=&#8221;no-extra-padding&#8221; column_padding_tablet=&#8221;inherit&#8221; column_padding_phone=&#8221;inherit&#8221; column_padding_position=&#8221;all&#8221; column_element_direction_desktop=&#8221;default&#8221; column_element_spacing=&#8221;default&#8221; desktop_text_alignment=&#8221;default&#8221; tablet_text_alignment=&#8221;default&#8221; phone_text_alignment=&#8221;default&#8221; background_color_opacity=&#8221;1&#8243; background_hover_color_opacity=&#8221;1&#8243; column_backdrop_filter=&#8221;none&#8221; column_shadow=&#8221;none&#8221; column_border_radius=&#8221;none&#8221; column_link_target=&#8221;_self&#8221; column_position=&#8221;default&#8221; gradient_direction=&#8221;left_to_right&#8221; overlay_strength=&#8221;0.3&#8243; width=&#8221;1\/1&#8243; tablet_width_inherit=&#8221;default&#8221; animation_type=&#8221;default&#8221; bg_image_animation=&#8221;none&#8221; border_type=&#8221;simple&#8221; column_border_width=&#8221;none&#8221; column_border_style=&#8221;solid&#8221;][vc_column_text text_direction=&#8221;default&#8221;]<strong>Sources<\/strong><\/p>\n<ul>\n<li>production endog\u00e8ne \u00e0 partir de l&#8217;acide glutamique par d\u00e9carboxylation en utilisant la vitamine B6 active et le magn\u00e9sium comme cofacteurs (synth\u00e8se stimul\u00e9e par l&#8217;exercice intense)<\/li>\n<li>alimentation : f\u00e8ves, l\u00e9gumes \u00e0 feuilles vertes, tomates, soja, noix et graines.<\/li>\n<li>production par le microbiome intestinal<\/li>\n<\/ul>\n<p><strong>Dosage<\/strong><\/p>\n<ul>\n<li>Pour les troubles du sommeil et de l&#8217;anxi\u00e9t\u00e9, des doses de 100 \u00e0 800 mg sont couramment utilis\u00e9es, \u00e9ventuellement r\u00e9parties sur plusieurs prises.<\/li>\n<\/ul>\n<p><strong>M\u00e9canisme de fonctionnement<\/strong><\/p>\n<ul>\n<li>neurotransmetteur inhibiteur calmant : le r\u00e9cepteur GABA A \u00e9quilibre l&#8217;activit\u00e9 et le repos. Le r\u00e9cepteur GABA B met fin \u00e0 l&#8217;hyperactivit\u00e9 c\u00e9r\u00e9brale. (Le GABA inhibe l&#8217;effet stimulant du glutamate)<\/li>\n<li>antioxydant<\/li>\n<li>stimule la production de prolactine<\/li>\n<li>relaxant musculaire naturel<\/li>\n<\/ul>\n<p>Le GABA peut difficilement traverser la barri\u00e8re h\u00e9mato-enc\u00e9phalique, mais il est souvent utilis\u00e9 avec des r\u00e9sultats positifs. Une explication pourrait \u00eatre que le GABA pr\u00e9sent en p\u00e9riph\u00e9rie a un effet positif sur le GABA dans le syst\u00e8me nerveux central (via l&#8217;axe intestin-cerveau).<\/p>\n<p><strong>S\u00e9curit\u00e9<\/strong><\/p>\n<ul>\n<li>Le GABA est bien tol\u00e9r\u00e9, ce qui a fait l&#8217;objet de plusieurs \u00e9tudes approfondies. Des doses \u00e9lev\u00e9es provoquent des naus\u00e9es, un essoufflement, de l&#8217;anxi\u00e9t\u00e9, des bouff\u00e9es de chaleur, une baisse de la tension art\u00e9rielle et des picotements dans les mains.<\/li>\n<li>Les \u00e9tudes sur les femmes enceintes et allaitantes sont insuffisantes.<\/li>\n<li>Attention \u00e0 l&#8217;interaction avec les m\u00e9dicaments hypotenseurs.<\/li>\n<\/ul>\n<p><strong>Applicable en cas de\u00a0<\/strong><\/p>\n<ul>\n<li>Stress et sympt\u00f4mes li\u00e9s au stress tels que l&#8217;hyperactivit\u00e9, l&#8217;anxi\u00e9t\u00e9, les maux de t\u00eate et l&#8217;irritabilit\u00e9.<\/li>\n<li>Insomnie<\/li>\n<\/ul>\n[\/vc_column_text][\/vc_column][\/vc_row][vc_row type=&#8221;in_container&#8221; full_screen_row_position=&#8221;middle&#8221; column_margin=&#8221;default&#8221; column_direction=&#8221;default&#8221; column_direction_tablet=&#8221;default&#8221; column_direction_phone=&#8221;default&#8221; scene_position=&#8221;center&#8221; text_color=&#8221;dark&#8221; text_align=&#8221;left&#8221; row_border_radius=&#8221;none&#8221; row_border_radius_applies=&#8221;bg&#8221; overflow=&#8221;visible&#8221; overlay_strength=&#8221;0.3&#8243; gradient_direction=&#8221;left_to_right&#8221; shape_divider_position=&#8221;bottom&#8221; bg_image_animation=&#8221;none&#8221;][vc_column column_padding=&#8221;no-extra-padding&#8221; column_padding_tablet=&#8221;inherit&#8221; column_padding_phone=&#8221;inherit&#8221; column_padding_position=&#8221;all&#8221; column_element_direction_desktop=&#8221;default&#8221; column_element_spacing=&#8221;default&#8221; desktop_text_alignment=&#8221;default&#8221; tablet_text_alignment=&#8221;default&#8221; phone_text_alignment=&#8221;default&#8221; background_color_opacity=&#8221;1&#8243; background_hover_color_opacity=&#8221;1&#8243; column_backdrop_filter=&#8221;none&#8221; column_shadow=&#8221;none&#8221; column_border_radius=&#8221;none&#8221; column_link_target=&#8221;_self&#8221; column_position=&#8221;default&#8221; gradient_direction=&#8221;left_to_right&#8221; overlay_strength=&#8221;0.3&#8243; width=&#8221;1\/1&#8243; tablet_width_inherit=&#8221;default&#8221; animation_type=&#8221;default&#8221; bg_image_animation=&#8221;none&#8221; border_type=&#8221;simple&#8221; column_border_width=&#8221;none&#8221; column_border_style=&#8221;solid&#8221;][image_with_animation image_url=&#8221;6754&#8243; image_size=&#8221;full&#8221; animation_type=&#8221;entrance&#8221; animation=&#8221;None&#8221; animation_movement_type=&#8221;transform_y&#8221; hover_animation=&#8221;none&#8221; alignment=&#8221;&#8221; border_radius=&#8221;none&#8221; box_shadow=&#8221;none&#8221; image_loading=&#8221;default&#8221; max_width=&#8221;100%&#8221; max_width_mobile=&#8221;default&#8221;][\/vc_column][\/vc_row]\n","protected":false},"excerpt":{"rendered":"<p>[vc_row type=&#8221;in_container&#8221; full_screen_row_position=&#8221;middle&#8221; column_margin=&#8221;default&#8221; column_direction=&#8221;default&#8221; column_direction_tablet=&#8221;default&#8221; column_direction_phone=&#8221;default&#8221; scene_position=&#8221;center&#8221; text_color=&#8221;dark&#8221; text_align=&#8221;left&#8221; row_border_radius=&#8221;none&#8221; row_border_radius_applies=&#8221;bg&#8221; overflow=&#8221;visible&#8221; overlay_strength=&#8221;0.3&#8243; gradient_direction=&#8221;left_to_right&#8221; shape_divider_position=&#8221;bottom&#8221; bg_image_animation=&#8221;none&#8221;][vc_column column_padding=&#8221;no-extra-padding&#8221; column_padding_tablet=&#8221;inherit&#8221; column_padding_phone=&#8221;inherit&#8221; column_padding_position=&#8221;all&#8221; column_element_direction_desktop=&#8221;default&#8221; column_element_spacing=&#8221;default&#8221; desktop_text_alignment=&#8221;default&#8221; tablet_text_alignment=&#8221;default&#8221; phone_text_alignment=&#8221;default&#8221; background_color_opacity=&#8221;1&#8243; background_hover_color_opacity=&#8221;1&#8243; column_backdrop_filter=&#8221;none&#8221; column_shadow=&#8221;none&#8221;&#8230;<\/p>\n","protected":false},"author":5,"featured_media":0,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[122],"tags":[],"class_list":["post-6750","post","type-post","status-publish","format-standard","category-solidpharma-nonpublic-be-fr"],"_links":{"self":[{"href":"https:\/\/www.solidpharma.be\/be-fr\/wp-json\/wp\/v2\/posts\/6750","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.solidpharma.be\/be-fr\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/www.solidpharma.be\/be-fr\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/www.solidpharma.be\/be-fr\/wp-json\/wp\/v2\/users\/5"}],"replies":[{"embeddable":true,"href":"https:\/\/www.solidpharma.be\/be-fr\/wp-json\/wp\/v2\/comments?post=6750"}],"version-history":[{"count":5,"href":"https:\/\/www.solidpharma.be\/be-fr\/wp-json\/wp\/v2\/posts\/6750\/revisions"}],"predecessor-version":[{"id":6793,"href":"https:\/\/www.solidpharma.be\/be-fr\/wp-json\/wp\/v2\/posts\/6750\/revisions\/6793"}],"wp:attachment":[{"href":"https:\/\/www.solidpharma.be\/be-fr\/wp-json\/wp\/v2\/media?parent=6750"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.solidpharma.be\/be-fr\/wp-json\/wp\/v2\/categories?post=6750"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.solidpharma.be\/be-fr\/wp-json\/wp\/v2\/tags?post=6750"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}